Gastroenterology

2018/10/02MEDICAL UPDATE

DDW 2018: Predicting who will get IBD

Interview by Hannah Chatfield To have a chance of preventing IBD clinicians need to be able to predict who is at risk, based on sensitive and selective risk factors. In a translational symposium at DDW 2018, speakers discussed the role of genetics, diet and environment in IBD aetiology.

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2018/10/02MEDICAL UPDATE

DDW 2018: Treatment of perianal fistulising disease

By Maria Dalby Perianal fistulas remain a debilitating complication for CD patients, with high levels of morbidity and impact on quality of life. Several abstracts and posters at DDW 2018 addressed the clinical management of perianal fistulas in CD.

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2018/10/02MEDICAL UPDATE

DDW 2018: IBD Study Updates

Interview by Hannah Chatfield This article summarises some of the key study updates presented at DDW 2018.

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2018/03/01MEDICAL UPDATE

ECCO 2018: Returning to a normal life with IBD

By Maria Dalby (article) and Peter Mas Mollinedo (interviews) Even with access to more potent and sophisticated drugs than ever before, IBD professionals still have a long way to go in optimising treatment and alleviating the long-term impact of the disease. Patient empowerment and patient-centred care are essential for reducing the burden of IBD; however, to achieve these clinicians must have a clear understanding of patients’ goals and perspectives...

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2018/03/01MEDICAL UPDATE

ECCO 2018: Evolving concepts of IBD pathogenesis

By Maria Dalby (articles) and Peter Mas Mollinedo (interviews) Perianal fistula is a debilitating complication in CD which affects up to 50% of patients in the course of their disease...

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2018/02/11MEDICAL UPDATE

ECCO 2018: Novel treatments in IBD

By Maria Dalby (article) and Peter Mas Mollinedo (interviews) The current research and development pipeline of novel biologic therapies and small molecule drugs promises improved efficacy and safety in the treatment of IBD in the near future. However, the complexity and heterogeneity of the disease means it is unlikely that one single therapy will meet all clinical needs; instead rational use of combination therapy and multidisciplinary management will provide a bridge to fully personalised therapy...

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2017/10/30MEDICAL UPDATE

ESCP 2017: Innovation in fistula management: sections and high-precision removal of the fistula epithelium 

by Maria Dalby Effective treatment options for perianal fistulas constitute a major unmet need in Crohn’sdisease (CD). New interventions included a knot-free silicon drain to replace conventional setons, and a circular blade that allows high-precision removal of the fistula epithelium prior to reparative surgery.

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2017/10/21MEDICAL UPDATE

ESCP Highlights 2017

[embed]http://vimeo.com/236913268[/embed] ESCP 2017 delegates give their highlights, plus a report on the ESCP/ECCO symposium on ulcerative colitis and a focus on quality of life for patients with perianal Crohn's disease.

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2017/10/11MEDICAL UPDATE

ESCP 2017: Multidisciplinary decision-making for colectomy: the difficult patient 

By Maria Dalby (article) and Peter Mas Mollinedo (interviews) The decision to perform a colectomy in patients with ulcerative colitis (UC) should not be made lightly. Such a decision should always be made within a multi-disciplinary team setting, and surgery should be considered not only for patients who are refractory to medical therapy or who need surgery, but also for…

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2017/10/03MEDICAL UPDATE

ESCP 2017: Innovations in fistula management: stem cell therapy

By Maria Dalby (article) and Peter Mas Mollinedo (interviews) In an overview of the immunological rationale for, and clinical application of adipose-derived mesenchymal stem cell (MSC) therapies, Dr Nick Powell  predicted that clinicians treating patients with perianal CD are going to be early uptakers of these therapies as they transition into clinical practice.

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